Coronavirus Update 117: Moderna vs. Pfizer COVID 19 Vaccine (mRNA vaccines)

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Professor Roger Seheult, MD discusses the Moderna COVID-19 mRNA vaccine: How it works and what we know about the safety, efficacy, and side effects at this time.

No mRNA vaccine has ever been approved by the FDA, but Moderna and Pfizer/BioNTech hope to receive emergency approval based on preliminary data from their ongoing vaccine trials.

Moderna's two-dose vaccine regimen does not require special refrigeration (the Pfizer vaccine is supposed to be stored at -70 Celcius) but a variety of questions remain:
Will the vaccine prevent transmission and asymptomatic spread?
How long will immunity last?
Will “ effective” hold up to peer-review and additional data when it is gathered?

(This video was recorded on November 17, 2020).

Dr. Seheult is the co-founder and lead instructor at


LINKS / REFERENCES:

Johns Hopkins Tracker |

Worldometer |

Outcomes for Out-of-Hospital Cardiac Arrest in the United States During the Coronavirus Disease 2019 Pandemic (JAMA Cardiology) |

Moderna’s Covid-19 vaccine is strongly effective, early look at data show (STAT) |

mRNA Platform: Enabling Drug Discovery & Development (Moderna) |

What is mRNA? (Moderna) |

Moderna’s COVID-19 Vaccine Candidate Meets its Primary Efficacy Endpoint in the First Interim Analysis of the Phase 3 COVE Study (Moderna) |


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Roger Seheult, MD
Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine.
Associate Professor at the University of California, Riverside School of Medicine

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Video Produced by Kyle Allred

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